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Micronase (Glyburide)

Generic name: Glyduride

Other brand names: DiaBeta, Glynase


Always remember that Micronase is an aid to, not a substitute for, good diet and exercise. Failure to follow a sound diet and exercise plan can lead to serious complications, such as dangerously high or low blood sugar levels. Remember, too, that Micronase is not an oral form of insulin, and cannot be used in place of insulin.

More common side effects may include:
Bloating, heartburn, nausea

Less common or rare side effects may include:
Anemia and other blood disorders, blurred vision, changes in taste, headache, hives, itching, joint pain, liver problems, muscle pain, reddening of the skin, skin eruptions, skin rash, yellowing of the skin

Micronase, like all oral antidiabetics, may cause hypoglycemia (low blood sugar) especially in elderly, weak, and udernourished people, and those with kidney, liver, adrenal, or pituitary gland problems. The rish of hypoglycemia can be increased by missed meals, alcohol, other medications, fever, trauma, infection, surgery, or excessive exercise. To avoid hypoglycemia, you should closely follow the dietary and exercise plan suggeted by your physician.

Symptoms of mild hypoglycemia may include:
Cold sweat, drowsiness, fast heartbeat, headache, nausea, nervousness

Symptoms of more severe hypoglycemia may include:
Coma, pale skin, seizures, shallow breathing

Eating sugar or a sugar-based product will often correct mild hypoglycemia.

Severe hypoglycemia should be considered a medical emergency, and prompt medical attention is essential.

Special warnings about this medication:
It’s possible that drugs such as Micronase may lead to more heart problems than diet treatment alone, or diet plus insulin. If you have a heart condition, you may want to discuss this with your doctor.

If you are taking Micronase, you should check your blood or urine periodically for abnornal sugar (glucose) levels.

It is important that you closely follow the diet and exercise plan recommended by your doctor.

The effectiveness of any oral antidiabetic, including Micronase, may decrease with time. This may occur either because of a diminished responsiveness to the medication or a worseing of the diabetes.

The "PHYSICIAN'S DESK REFERENCE®", and PDR® are registered trademarks owned by Medical Economics.

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